Onyx extravasation is a rare complication during embolization of arteriovenous malformations (AVM). We present a case of embolization complicated by Onyx leak into the cerebellum later encountered during surgical excision of the AVM. Our goal is to report on these rare events and to outline the successful treatment of this complication.
patient records are reviewed for medical history, laboratory and radiological examinations, and outpatient follow-up clinics. A 62-year-old woman presented with a hunting Hess modified grade 2 and grade Fisher 2 subarachnoid hemorrhage (SAH) secondary to a ruptured left lower posterior cerebellar artery (PICA) aneurysm associated with vermian superior cerebellar AVM.
After endovascular intervention, totally embolized aneurysm; However, only 75% of the AVM can be safely eliminated. Onyx extravasation of aneurysm rupture was recorded on the first angiogram. Elective suboccipital craniectomy then planned for residual AVM resection where extravasated Onyx caused a disturbance during resection surgery. Post-op angiogram confirmed complete resection of the AVM, as well as most of the extravasated Onyx. Patients did well post-surgery, neurological residual intact during the course of the hospital.
Although rarely reported in the literature, Onyx extravasation is a potential complication that neurosurgeons have to be prepared to face. Compliance of Onyx into the surrounding parenchyma could inhibit optimal surgical resection of AVM and increased complications. Therefore, careful surgical dissection should be done with special care for delicate neurovasculature. In this case, a complete resection of the AVM and the mass of the Onyx safely reached.
 TRIS |
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| GP7166-250G | Glentham Life Sciences | 250 g | EUR 52.00 |
TRIS |
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| GP7166-500G | Glentham Life Sciences | 500 g | EUR 60.00 |
 Tris |
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| 16-0021-500 | Medicago | 500 g | EUR 85.00 |
TRIS |
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| CH058 | ABM | 500 g | EUR 138.00 |
TRIS |
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| CH059 | ABM | 1kg (2 x 500g [CH058]) | EUR 157.00 |
TRIS |
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| CH060 | ABM | 5kg (10 x 500g [CH058]) | EUR 379.00 |
Tris |
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| TB0197 | BBI Biotech | 500g | EUR 86.25 |
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 TRIS hydrochloride |
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| B7299-500000 | ApexBio | 500 g | EUR 258.00 |
 Tris DBA |
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| B7402-50 | ApexBio | 50 mg | EUR 145.00 |
 BIS-TRIS |
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| B7772-100000 | ApexBio | 100 g | EUR 268.00 |
 Bis-Tris |
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| BB0079 | BBI Biotech | 25g | EUR 62.18 |
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 Fostemsavir Tris |
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| HY-15440B | MedChemExpress | 5mg | EUR 257.00 |
TRIS hydrochloride |
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| GB4431-100G | Glentham Life Sciences | 100 g | EUR 54.00 |
TRIS hydrochloride |
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| GB4431-1KG | Glentham Life Sciences | 1 kg | EUR 134.00 |
TRIS hydrochloride |
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| GB4431-250G | Glentham Life Sciences | 250 g | EUR 64.00 |
TRIS hydrochloride |
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| GB4431-500G | Glentham Life Sciences | 500 g | EUR 86.00 |
TRIS hydrochloride |
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| GB4431-5KG | Glentham Life Sciences | 5 kg | EUR 405.00 |
BIS-TRIS |
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| GB6605-100G | Glentham Life Sciences | 100 g | EUR 78.00 |
BIS-TRIS |
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| GB6605-1KG | Glentham Life Sciences | 1 kg | EUR 341.00 |
BIS-TRIS |
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| GB6605-250G | Glentham Life Sciences | 250 g | EUR 126.00 |
BIS-TRIS |
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| GB6605-25G | Glentham Life Sciences | 25 g | EUR 50.00 |
BIS-TRIS |
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| GB6605-500G | Glentham Life Sciences | 500 g | EUR 205.00 |
 TRIS acetate |
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| GB8936-500G | Glentham Life Sciences | 500 g | EUR 285.00 |
 Tris-Phenolis |
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| abx082108-250ml | Abbexa | 250 ml | EUR 189.00 |
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 Tris-base |
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| 20-abx082498 | Abbexa |
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 Tris-Hcl |
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| 20-abx082568 | Abbexa |
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 250G Tris |
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| NAT1050 | National Diagnostics | 250G | EUR 85.00 |
Tris-Hcl |
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| T9201-100 | GenDepot | 1Kg | EUR 296.00 |
 Tris hydrochloride |
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| TB0103 | BBI Biotech | 250g | EUR 70.01 |
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 Tris acetate |
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| TD0101 | BBI Biotech | 100g | EUR 85.96 |
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 IgG1, aff pure (w/o azide)) Rat Monoclonal Anti-Dinitrophenyl (DNP) IgG1, aff pure (w/o azide) |
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| DNP15-MW | Alpha Diagnostics | 100 ug | EUR 445.00 |
 Bis-Tris Propane |
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| BB0238 | BBI Biotech | 50g | EUR 107.42 |
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 Ketorolac tris salt |
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| GP8482-100MG | Glentham Life Sciences | 100 mg | EUR 75.00 |
 BIS-TRIS hydrochloride |
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| GK3758-100G | Glentham Life Sciences | 100 g | EUR 181.00 |
BIS-TRIS hydrochloride |
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| GK3758-250G | Glentham Life Sciences | 250 g | EUR 317.00 |
BIS-TRIS hydrochloride |
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| GK3758-25G | Glentham Life Sciences | 25 g | EUR 82.00 |
 BIS-TRIS propane |
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| GB2945-100G | Glentham Life Sciences | 100 g | EUR 150.00 |
BIS-TRIS propane |
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| GB2945-250G | Glentham Life Sciences | 250 g | EUR 269.00 |
BIS-TRIS propane |
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| GB2945-25G | Glentham Life Sciences | 25 g | EUR 70.00 |
BIS-TRIS propane |
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| GB2945-500G | Glentham Life Sciences | 500 g | EUR 469.00 |
 1KG Tris Ultrapure |
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| NAT1052 | National Diagnostics | 1KG | EUR 148.00 |
 Bis-Tris, 250g |
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| R6976-250g | ACTGene | EUR 190.00 | |
 Bis-Tris, 500g |
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| R6976-500g | ACTGene | EUR 309.00 | |
 Tris - Biotech Grade |
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| TB0196 | BBI Biotech | 500g | EUR 71.75 |
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 propane) Tris-(hydroxymethyl) propane |
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| T1491 | BBI Biotech | 100g | EUR 75.23 |
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 Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl |
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| T8059-010 | GenDepot | 100ml | EUR 76.00 |
Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl |
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| T8059-050 | GenDepot | 500ml | EUR 84.00 |
Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl |
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| T8059-101 | GenDepot | 1L | EUR 126.00 |
Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl |
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| T8150-050 | GenDepot | 500 ml | EUR 84.00 |
Tris EDTA Saline, 10mM Tris HCl , 1mM EDTA, 2M Nacl |
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| T8150-801 | GenDepot | 8L | EUR 120.00 |
) Tris (Molecular Biology Grade) |
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| CE237 | GeneOn | 500 g | EUR 89.00 |
Tris (Molecular Biology Grade) |
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| CE238 | GeneOn | 1 kg | EUR 128.00 |
Tris (Molecular Biology Grade) |
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| CE239 | GeneOn | 5 kg | EUR 446.00 |
 1.5M Tris-HCI,pH8.8 |
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| AR1162 | BosterBio | 100mL | EUR 60.00 |
 1M Tris-HCI,pH6.8 |
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| AR1163 | BosterBio | 100mL | EUR 60.00 |
 borate) tris(2,2,2-trifluoroethyl) borate |
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| B8211-10 | ApexBio | 10 mg | EUR 108.00 |
tris(2,2,2-trifluoroethyl) borate |
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| B8211-50 | ApexBio | 50 mg | EUR 189.00 |
methane) Tris(4-aminophenyl)methane |
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| HY-D0306 | MedChemExpress | 500mg | EUR 187.00 |
 aminomethane) Bis-tris (hydroxymethyl) aminomethane |
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| abx082231-5g | Abbexa | 5 g | EUR 175.00 |
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dipalladium(0)) Tris(dibenzylideneacetone)dipalladium(0) |
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| 20-abx184467 | Abbexa |
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ethane) 1,1,1-Tris(hydroxymethyl)ethane |
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| 20-abx186111 | Abbexa |
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 Borate) Tris(2,2,2-trifluoroethyl) Borate |
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| 20-abx182700 | Abbexa |
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) CEA protein (in TRIS) |
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| 30-AC26 | Fitzgerald | 1 mg | EUR 414.00 |
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Description: Purified native Human CEA protein |
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) Tris-HCl (pH 6.8) |
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| 2106-100 | Biovision | EUR 137.00 | |
) Tris-HCl (pH 8.8) |
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| 2107-100 | Biovision | EUR 137.00 | |
 SDS-Urea-Tris solution |
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| SB8896 | BBI Biotech | 500ml | EUR 74.36 |
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) 0.5M Tris Buffer (pH6.8) |
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| T8102-010 | GenDepot | 100ml | EUR 80.00 |
0.5M Tris Buffer (pH6.8) |
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| T8102-050 | GenDepot | 500ml | EUR 88.00 |
0.5M Tris Buffer (pH6.8) |
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| T8102-100 | GenDepot | 2x500ml | EUR 101.00 |
 Tris Base, Ultra Pure |
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| T9200-100 | GenDepot | 1kg | EUR 167.00 |
 Tris Base , Ultra Pure |
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| T9200-500 | GenDepot | 5kg | EUR 516.00 |
 Tris - Ultra Pure Grade |
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| TB0194 | BBI Biotech | 500g | EUR 74.36 |
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 1 L 1M TRIS-HYDROCHLORIDE BUFFERS, 1M TRIS-HCI, PH 7.5, LIQUID |
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| 46-030-CM | CORNING | 1L/pk | EUR 138.00 |
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Description: Media Catalog; Classical Media |
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 1 L 1M TRIS-HYDROCHLORIDE BUFFERS, 1M TRIS-HCI, PH 8.0, LIQUID |
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| 46-031-CM | CORNING | 1L/pk | EUR 138.00 |
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Description: Media Catalog; Classical Media |
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) Tris - Hydrochloride (Molecular Biology Grade) |
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| CE234 | GeneOn | 250 g | EUR 83.00 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE235 | GeneOn | 500 g | EUR 120.00 |
Tris - Hydrochloride (Molecular Biology Grade) |
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| CE236 | GeneOn | 1 kg | EUR 186.00 |
 Powder) Tris Buffered Saline (TBS) Powder |
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| AR0031 | BosterBio | 2000mL/pack | EUR 53.00 |
 Tris-Glycine SDS Buffer Pack |
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| AR1149 | BosterBio | 1L/pack | EUR 55.00 |
) Primary Antibody Diluent (Tris, Green) |
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| ATG-20000 | ScyTek Laboratories | 20 L | EUR 1177.00 |
Primary Antibody Diluent (Tris, Green) |
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| ATG125 | ScyTek Laboratories | 125 ml | EUR 74.00 |
Primary Antibody Diluent (Tris, Green) |
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| ATG500 | ScyTek Laboratories | 500 ml | EUR 101.00 |
Primary Antibody Diluent (Tris, Green) |
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| ATG999 | ScyTek Laboratories | 1000 ml | EUR 124.00 |
 10x Tris-Glycine Buffer Solution |
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| BA01806 | Bioatlas | 6x100ml | EUR 97.00 |
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Description: High purity buffer for various PCR applications. |
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) Normal Antibody Diluent (Tris Buffered) |
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| ADT125 | ScyTek Laboratories | 125 ml | EUR 74.00 |
Normal Antibody Diluent (Tris Buffered) |
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| ADT500 | ScyTek Laboratories | 500 ml | EUR 101.00 |
Normal Antibody Diluent (Tris Buffered) |
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| ADT999 | ScyTek Laboratories | 1000 ml | EUR 124.00 |
phosphine hydrochloride) Tris-(2-carboxyethyl)phosphine hydrochloride |
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| GE1860-10G | Glentham Life Sciences | 10 g | EUR 221.00 |
Tris-(2-carboxyethyl)phosphine hydrochloride |
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| GE1860-1G | Glentham Life Sciences | 1 g | EUR 78.00 |
Tris-(2-carboxyethyl)phosphine hydrochloride |
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| GE1860-25G | Glentham Life Sciences | 25 g | EUR 389.00 |
Tris-(2-carboxyethyl)phosphine hydrochloride |
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| GE1860-5G | Glentham Life Sciences | 5 g | EUR 150.00 |
-1,3,5-triazine) 2,4,6-Tris(trichloromethyl)-1,3,5-triazine |
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| 20-abx186181 | Abbexa |
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 450ML 20X Tris-MOPS SDS |
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| NAT1210 | National Diagnostics | 450ML | EUR 109.00 |
 450ML 20X Tris-MEPS SDS |
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| NAT1212 | National Diagnostics | 450ML | EUR 109.00 |
 10X Tris-Glycine SDS buffer |
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| T8053-050 | GenDepot | 500ml | EUR 85.00 |
10X Tris-Glycine SDS buffer |
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| T8053-100 | GenDepot | 2X500ml | EUR 111.00 |
10X Tris-Glycine SDS buffer |
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| T8053-101 | GenDepot | 1L | EUR 99.00 |
10X Tris-Glycine SDS buffer |
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| T8053-104 | GenDepot | 4 L | EUR 153.00 |
10X Tris-Glycine SDS buffer |
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| T8053-200 | GenDepot | 4X500ml | EUR 136.00 |
10X Tris-Glycine SDS buffer |
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| T8053-201 | GenDepot | 2X1L | EUR 135.00 |
10X Tris-Glycine SDS buffer |
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| T8053-401 | GenDepot | 4X1L | EUR 172.00 |
) 1.5M Tris Buffer (pH 8.8) |
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| T8101-010 | GenDepot | 100ml | EUR 80.00 |
1.5M Tris Buffer (pH 8.8) |
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| T8101-050 | GenDepot | 500ml | EUR 88.00 |
1.5M Tris Buffer (pH 8.8) |
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| T8101-100 | GenDepot | 2x500ml | EUR 101.00 |
 Tris-HCl, 1M, 1XpH 7.4 |
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| USD8125 | BBI Biotech | 500ml | EUR 77.84 |
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 Salt) Phosphoenolpyruvic Acid Tris(cyclohexylammonium) Salt |
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| B2675-100 | Biovision | 100mg | EUR 125.00 |
Phosphoenolpyruvic Acid Tris(cyclohexylammonium) Salt |
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| B2675-500 | Biovision | 500mg | EUR 318.00 |
 MW-150 |
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| HY-120111 | MedChemExpress | 10mM/1mL | EUR 492.00 |
 concentrate (10X, 50 mM Tris, pH 7.4 final)) Tris Buffer (TB, pH 7.4) concentrate (10X, 50 mM Tris, pH 7.4 final) |
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| 80083-W | Alpha Diagnostics | 1 L | EUR 225.00 |
 concentrate (10X, 100 mM Tris/150mM NaCl final)) Tris Buffered Saline (TBS, pH 7.4) concentrate (10X, 100 mM Tris/150mM NaCl final) |
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| 80082 | Alpha Diagnostics | 1 L | EUR 225.00 |
 concentrate (10X, 50 mM Tris/150mM NaCl final)) Tris Buffered Saline (TBS, pH 7.4) concentrate (10X, 50 mM Tris/150mM NaCl final) |
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| 80083 | Alpha Diagnostics | 1 L | EUR 225.00 |
) 5X Bacterial Protein Extraction Reagent (Tris) |
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| AKR-180 | Cell Biolabs | 50mL | EUR 276.00 |
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Description: The Cell Biolabs Bacterial Protein Extraction Reagents contain a gentle, nonionic detergent formulation which quickly extracts functional, recombinant protein from E. coli without mechanical disruption. |
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 Tris-Glycine SDS Running Buffer Pack |
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| AR0139 | BosterBio | 1L/pack (for 5 assyas) | EUR 55.00 |
 10x Tris-Glycine Ready Mixed Powder |
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| BA01707 | Bioatlas | 1L | EUR 85.00 |
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Description: High purity buffer for various PCR applications. |
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 10x Tris-Glycine-SDS Buffer Solution |
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| BA01807 | Bioatlas | 6x100ml | EUR 103.00 |
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Description: High purity buffer for various PCR applications. |
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 TRIS Ultrapure, 99.9%, Ph. Eur. grade |
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| GB1923-100G | Glentham Life Sciences | 100 g | EUR 54.00 |
TRIS Ultrapure, 99.9%, Ph. Eur. grade |
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| GB1923-1KG | Glentham Life Sciences | 1 kg | EUR 190.00 |
TRIS Ultrapure, 99.9%, Ph. Eur. grade |
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| GB1923-250G | Glentham Life Sciences | 250 g | EUR 79.00 |
TRIS Ultrapure, 99.9%, Ph. Eur. grade |
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| GB1923-500G | Glentham Life Sciences | 500 g | EUR 118.00 |
Methane, 70% in water) Tris(trifluoroMethanesulfonyl)Methane, 70% in water |
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| 20-abx185605 | Abbexa |
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Methyl]Aniline) 4-[Tris(4-Aminophenyl)Methyl]Aniline |
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| 20-abx188428 | Abbexa |
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-dipalladium(O)-chloroform adduct) Tris-(dibenzylideneacetone)-dipalladium(O)-chloroform adduct |
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| 20-abx182701 | Abbexa |
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[1,3,5]triazine) 2,4,6-Tris-(4-bromophenyl)[1,3,5]triazine |
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| 20-abx182980 | Abbexa |
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) 10 x TBE (Tris/Borate/EDTA) |
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| A00269 | BBI Biotech | 500ml | EUR 56.36 |
|
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 10X Solution) TG Buffer (TRIS-GLYCINE) 10X Solution |
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| A0028 | BBI Biotech | 4L | EUR 94.80 |
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 Tris buffer pH 7.4, 1000 ml |
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| 12-9198-10 | Medicago | 1000 ml | EUR 283.00 |
 Tris buffer pH 8.0, 1000 ml |
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| 12-9199-10 | Medicago | 1000 ml | EUR 283.00 |
 Tris buffer pH 8.3, 1000 ml |
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| 12-9200-10 | Medicago | 1000 ml | EUR 283.00 |
 Buffer (50X)) TAE (Tris-Acetate-EDTA) Buffer (50X) |
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| 2116-500 | Biovision | EUR 120.00 | |
 100 G TRIS BASE BUFFER, POWDER |
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| 61-233-RM | CORNING | 100 g/pk | EUR 136.00 |
|
Description: Media Catalog; Buffered Salt-Salution |
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 1000 G TRIS BASE BUFFER, POWDER |
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| 61-233-RR | CORNING | 1000 g/pk | EUR 182.00 |
|
Description: Media Catalog; Buffered Salt-Salution |
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 5000 G TRIS BASE BUFFER, POWDER |
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| 61-233-RT | CORNING | 5000 g/pk | EUR 434.00 |
|
Description: Media Catalog; Buffered Salt-Salution |
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 1L Tris-Glycine Electroblotting Buffer 10X |
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| NAT1240 | National Diagnostics | 1L | EUR 85.00 |
 4L Tris-Glycine Electroblotting Buffer 10X |
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| NAT1242 | National Diagnostics | 4L | EUR 121.00 |
 Tris Buffered Saline) 1L TBS (10X) Tris Buffered Saline |
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| NAT1244 | National Diagnostics | 1L | EUR 105.00 |
 1L Tris-HCL 1M pH 7.2 |
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| NAT1290 | National Diagnostics | 1L | EUR 105.00 |
 1L Tris-HCL 1M pH 7.4 |
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| NAT1292 | National Diagnostics | 1L | EUR 105.00 |
 1L Tris-HCL 1M pH 7.6 |
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| NAT1294 | National Diagnostics | 1L | EUR 105.00 |
) Tris-Triton Cell Lysis Buffer(1X) |
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| T8200-100 | GenDepot | 100ml | EUR 126.00 |